Amnestic mild cognitive impairment individuals with dissimilar pathologic origins show common regional vulnerability in the default mode network
Abstract
Alzheimer's and Parkinson's disease (AD and PD) are distinct disorders but share similar biomarker profiles. The regions of the default mode network are implicated in these diseases and are associated with amnestic symptoms. The role of apolipoprotein‐ε4 (APOE‐ε4), which is associated with cognitive function, is unclear in PD.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2018
- Source ID
- 10.1016/j.dadm.2018.08.004
Entities
People
- Daniel O. Claassen
- Manus J. Donahue
- Swati Rane
Organizations
- AbbVie
- Alzheimer's Disease Neuroimaging Initiative
- Avid Radiopharmaceuticals
- BioClinica
- Biogen
- Canadian Institutes of Health Research
- Chiron Corporation
- Eli Lilly and Company
- GE HealthCare
- Hoffmann-La Roche
- Laboratoires Servier
- Lundbeck
- Merck & Co.
- National Institute of Biomedical Imaging and Bioengineering
- National Institute on Aging
- National Institutes of Health
- Norman Cousins Center for Psychoneuroimmunology
- Pfizer
- Roche (United States)
- Takeda Pharmaceutical Company
- The Michael J. Fox Foundation
- The W. Garfield Weston Foundation
- United States Department of Defense
- University of Washington
- Vanderbilt University