Improved protocol for measurement of plasma β‐amyloid in longitudinal evaluation of Alzheimer's Disease Neuroimaging Initiative study patients
Abstract
The interassay variability and inconsistency of plasma β‐amyloid (Aβ) measurements among centers are major factors precluding the interpretation of results and a substantial obstacle in the meta‐analysis across studies of this biomarker. The goal of this investigation was to address these problems by improving the performance of the bioanalytical method.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 01, 2012
- Source ID
- 10.1016/j.jalz.2012.01.001
Entities
People
- Hugo Vanderstichele
- John Q. Trojanowski
- Jon Toledo
- Leslie M. Shaw
- Magdalena Korecka
- Michal J. Figurski
- Teresa Waligorska
- Virginia M.y. Lee
Organizations
- Foundation for the National Institutes of Health
- National Institute of Biomedical Imaging and Bioengineering
- University of Pennsylvania