Development of a straightforward and sensitive scale for MCI and early AD clinical trials

Abstract

Although the Clinical Dementia Rating Scale‐Sum of Boxes score (CDR‐SB) is a widely accepted and commonly used global scale, validated clinical endpoints of cognitive changes are unavailable in the predementia stages of Alzheimer's disease (AD), and a new clinical assessment with reliability and sensitivity is needed in the mild cognitive impairment (MCI) population.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 08, 2014
Source ID
10.1016/j.jalz.2014.03.008

Entities

People

  • Clare B. Billing Jr.
  • Kaori L. Ito
  • Richard J. Anziano
  • The Alzheimer’s Disease Neuroimaging Initiative*
  • Yifan Huang

Organizations

  • National Institute on Aging
  • National Institutes of Health
  • Pfizer

Tags

Fields of Study

  • Medicine
  • Psychology

Readers

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  • Regression Analysis.
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