Synergistic interaction between amyloid and tau predicts the progression to dementia

Abstract

Recent literature proposes that amyloid β (Aβ) and phosphorylated tau (p‐tau) synergism accelerates biomarker abnormalities in controls. Yet, it remains to be answered whether this synergism is the driving force behind Alzheimer disease (AD) dementia.

Document Details

Document Type
Pub Defense Publication
Publication Date
Dec 23, 2016
Source ID
10.1016/j.jalz.2016.11.005

Entities

People

  • Andrea L Benedet
  • Aurelie Labbe
  • Jean‐paul Soucy
  • Min Su Kang
  • Monica Shin
  • Pedro Rosa‐neto
  • Sara Mohades
  • Seqian Wang
  • Serge Gauthier
  • Sulantha Mathotaarachchi
  • Tharick A Pascoal
  • Tom Beaudry

Organizations

  • Alzheimer's Association
  • Canadian Institutes of Health Research
  • McGill University
  • McGill University Health Centre
  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • United States Department of Defense

Tags

Readers

  • Joint Military Operations and Doctrine.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.