Family history and TOMM40 '523 interactive associations with memory in middle‐aged and Alzheimer's disease cohorts

Abstract

Family history (FH) of Alzheimer's disease (AD) affects mitochondrial function and may modulate effects of translocase of the outer mitochondrial membrane 40 kDa (TOMM40) rs10524523 ('523) poly‐T length on memory decline.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 22, 2017
Source ID
10.1016/j.jalz.2017.03.009

Entities

People

  • Alexandra M Wennberg
  • Allen Roses
  • Auriel A. Willette
  • Barbara B Bendlin
  • Bruce P Hermann
  • Jennifer M. Oh
  • Joseph L. Webb
  • Michael W. Lutz
  • N. Maritza Dowling
  • Rebecca L. Koscik
  • Sanjay Asthana
  • Sterling C. Johnson

Organizations

  • Alzheimer's Disease Neuroimaging Initiative
  • Duke University
  • Geriatric Research Education and Clinical Center
  • Iowa State University
  • Mayo Clinic
  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • United States Department of Defense
  • University of Iowa
  • University of Wisconsin–Madison

Tags

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biochemistry
  • Molecular and Cellular Biology
  • Political Science/ International Relations/ European Studies