CDK5RAP2 gene and tau pathophysiology in late‐onset sporadic Alzheimer's disease

Abstract

Because currently known Alzheimer's disease (AD) single‐nucleotide polymorphisms only account for a small fraction of the genetic variance in this disease, there is a need to identify new variants associated with AD.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jan 19, 2018
• Source ID: 10.1016/j.jalz.2017.12.004

Entities

People

• Cynthia Picard
• Doris Dea
• Josée Frappier
• Judes Poirier
• Justin Miron
• Louise Théroux
• Nathalie Nilsson
• The Alzheimer’s Disease Neuroimaging Initiative*
• United Kingdom Brain Expression Consortium

Organizations

• Alzheimer's Association
• Alzheimer's Research UK
• Canadian Institutes of Health Research
• Douglas Mental Health University Institute
• McGill University
• Medical Research Council
• National Heart, Lung, and Blood Institute
• National Institutes of Health
• Natural Sciences and Engineering Research Council
• United States Department of Defense
• Wellcome Trust

Tags

Fields of Study

• Biology

Readers

• Molecular and genetic basis of cancer.
• Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.

Technology Areas

• Biotechnology