Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease

Abstract

Individuals in early stages of Alzheimer's disease are a targeted population for secondary prevention trials aimed at preserving normal cognition. Understanding within‐person biomarker(s) change over time is critical for trial enrollment and design.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 24, 2018
Source ID
10.1016/j.jalz.2018.01.012

Entities

People

  • Anne M. Fagan
  • Chengjie Xiong
  • Courtney L. Sutphen
  • David M. Holtzman
  • Elizabeth M. Herries
  • Jack H. Ladenson
  • Lena Mccue
  • On Behalf Of Adni

Organizations

  • National Institute of Biomedical Imaging and Bioengineering
  • National Institute on Aging
  • National Institutes of Health
  • Northern California Institute for Research and Education
  • United States Department of Defense
  • Washington University in St. Louis

Tags

Fields of Study

  • Psychology

Readers

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