Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
Abstract
Bile acids (BAs) are the end products of cholesterol metabolism produced by human and gut microbiome co‐metabolism. Recent evidence suggests gut microbiota influence pathological features of Alzheimer's disease (AD) including neuroinflammation and amyloid‐β deposition.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 15, 2018
- Source ID
- 10.1016/j.jalz.2018.08.012
Entities
People
- Alexandra Kueider‐paisley
- Andrew J. Saykin
- Colette Blach
- Cornelia M. Van Duijn
- For The Alzheimer's Disease Neuroimaging Initiative And The Alzheimer Disease Metabolomics Consortium
- Gabi Kastenmüller
- Gregory Louie
- Guoxiang Xie
- John Q. Trojanowski
- Kwangsik Nho
- Leslie M. Shaw
- Matthias Arnold
- Michael W. Weiner
- P. Murali Doraiswamy
- Rebecca Baillie
- Rima Kaddurah‐daouk
- Shahzad Ahmad
- Shannon L. Risacher
- Siamak Mahmoudiandehkordi
- Thomas Hankemeier
- Wei Jia
- Xianlin Han
Organizations
- Duke University
- Erasmus MC
- Helmholtz Zentrum München
- Indiana University School of Medicine
- Leiden University
- National Institute of Biomedical Imaging and Bioengineering
- National Institute on Aging
- National Institutes of Health
- Northern California Institute for Research and Education
- United States Department of Defense
- United States National Library of Medicine
- University of California, San Francisco
- University of Hawaiʻi System
- University of Pennsylvania
- University of Texas at Austin