Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH‐EXAMINER as a potential clinical trial endpoint
Abstract
Identifying clinical measures that track disease in the earliest stages of frontotemporal lobar degeneration (FTLD) is important for clinical trials. Familial FTLD provides a unique paradigm to study early FTLD. Executive dysfunction is a clinically relevant hallmark of FTLD and may be a marker of disease progression.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2020
- Source ID
- 10.1016/j.jalz.2019.01.012
Entities
People
- Adam L. Boxer
- Adam M. Staffaroni
- Alex Pantelyat
- Amy Wolf
- Ann Fishman
- Anna Karydas
- Arthur W. Toga
- Behnaz Ghazanfari
- Bonnie Wong
- Brad F. Boeve
- Bradford C. Dickerson
- Brian Appleby
- Bruce L. Miller
- Chiadi Onyike
- Christina Caso
- Christina Dheel
- Codrin Lungu
- Dana Haley
- Daniel I. Kaufer
- Danielle Brushaber
- David J. Irwin
- David S. Knopman
- David T. Jones
- Debra Gearhart
- Diana R. Kerwin
- Diane Lucente
- Edward D. Huey
- Eliana Marisa Ramos
- Emily Mckinley
- Emily Rogalski
- Erik D. Roberson
- Fanny M. Elahi
- Ging‐yuek Hsiung
- Giovanni Coppola
- Hilary W. Heuer
- Howard J. Rosen
- Ian Grant
- Ian R. Mackenzie
- Irene Litvan
- Jamie Fong
- Jaya Padmanabhan
- Jeremy Syrjanen
- Jessica Bove
- Jessica Ferrall
- Jill Goldman
- Joanne Taylor
- Joel H. Kramer
- John Kornak
- John Q. Trojanowski
- Jonathan Graff‐radford
- Julie A. Fields
- Katherine P. Rankin
- Katya Rascovsky
- Kejal Kantarci
- Kelly Faber
- Kimiko Domoto‐reilly
- Leah K. Forsberg
- Len Petrucelli
- Leslie M. Shaw
- Lynn Bajorek
- Lynne Jones
- M. Carmela Tartaglia
- Madeline Potter
- Mario F. Mendez
- Masood Manoochehri
- Miranda Maldonado
- Murray Grossman
- Nadine Tatton
- Namita Multani
- Neill Graff‐radford
- Nupur Ghoshal
- On Behalf Of The Artfl/lefftds Consortium
- Patrick Brannelly
- Peter A. Ljubenkov
- Pheth Sengdy
- Ping Wang
- Ralitza Gavrilova
- Reilly Dever
- Rodney Pearlman
- Rosa Rademakers
- Ruth Kraft
- Sandra Weintraub
- Scott M. Mcginnis
- Sheng‐yang M. Goh
- Sophia Dominguez
- Susan Dickinson
- Tatiana Foroud
- Vahan Aslanyan
- Walter A. Kukull
- Walter K. Kremers
- Yann Cobigo
- Yvette Bordelon
- Zbigniew K Wszolek
Organizations
- AbbVie
- Allergan, Inc.
- Alzheimer Society of B.C.
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Association for Frontotemporal Degeneration
- AstraZeneca
- Biogen
- BrightFocus Foundation
- Bristol-Myers Squibb
- Canadian Institutes of Health Research
- Centers for Disease Control and Prevention
- Eisai
- GE HealthCare
- Hoffmann-La Roche
- Huntington's Disease Society of America
- Janssen Pharmaceuticals
- Larry L. Hillblom Foundation
- Merck & Co.
- National Institute of Neurological Disorders and Stroke
- National Institute on Aging
- National Institutes of Health
- New York State Department of Health
- Pfizer
- Roche (United States)
- Swedish Parkinson’s Disease Association
- The Michael J. Fox Foundation
- United States Department of Defense
- University of Southern California
- Wyeth