In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid‐negative individuals
Abstract
It is unclear the degree to which tau pathology in the medial temporal lobe (MTL) measured by 18F‐flortaucipir positron emission tomography relates to MTL subregional atrophy and whether this relationship differs between amyloid‐β–positive and amyloid‐β–negative individuals.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 06, 2019
- Source ID
- 10.1016/j.jalz.2019.05.009
Entities
People
- David A. Wolk
- Laura E.m. Wisse
- Long Xie
- Nicolas Vergnet
- Paul A. Yushkevich
- Ranjit Ittyerah
- Salena Cui
- Sandhitsu R. Das
- The Alzheimer’s Disease Neuroimaging Initiative*
Organizations
- Alzheimer's Disease Neuroimaging Initiative
- BrightFocus Foundation
- National Institute of Biomedical Imaging and Bioengineering
- National Institute on Aging
- National Institutes of Health
- Thomas Jefferson University
- United States Department of Defense
- University of Pennsylvania