The effect of diagnostic criteria on outcome measures in preclinical and prodromal Alzheimer's disease: Implications for trial design
Abstract
We investigated the influence of different inclusion criteria for preclinical and prodromal Alzheimer's disease (AD) on changes in biomarkers and cognitive markers and on trial sample size estimates.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 30, 2017
- Source ID
- 10.1016/j.trci.2017.08.005
Entities
People
- Betty M. Tijms
- Daniela Bertens
- Lisa Vermunt
- Niels D. Prins
- Philip Scheltens
- Pieter Jelle Visser
- The Alzheimer’s Disease Neuroimaging Initiative*
Organizations
- National Institute of Biomedical Imaging and Bioengineering
- National Institute on Aging
- National Institutes of Health
- United States Department of Defense