Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 17, 2022
Source ID
10.1021/acsbiomedchemau.2c00034

Entities

People

  • Benjamin E. Nilsson-payant
  • Benjamin R tenOever
  • Derek Shore
  • Hao Wu
  • Harel Weinstein
  • Nora Hassan
  • Robert E. Schwartz
  • Saloni Sinha
  • Shuibing Chen
  • Vasuretha Chandar
  • Xiaohua Duan
  • Yaron Bram
  • Álvaro Fajardo

Organizations

  • Defense Advanced Research Projects Agency
  • Department of Surgery
  • Division of Intramural Research, National Institute of Allergy and Infectious Diseases
  • Icahn School of Medicine at Mount Sinai
  • Irma T. Hirschl Trust
  • National Institute of Diabetes and Digestive and Kidney Diseases
  • Weill Cornell Medicine