Enhanced Degradation of Mutant C9ORF72-Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 04, 2023
- Source ID
- 10.1021/acschemneuro.2c00732
Entities
People
- Allison S. Vanecek
- Jelena Mojsilovic-petrovic
- Jetze J Tepe
- Robert G. Kalb
Organizations
- Les Turner ALS Foundation
- Michigan State University
- National Institute on Aging
- Northwestern University
- United States Army
- United States Public Health Service