ANO7 African-ancestral genomic diversity and advanced prostate cancer

Abstract

Prostate cancer (PCa) is a significant health burden for African men, with mortality rates more than double global averages. The prostate specific Anoctamin 7 (ANO7) gene linked with poor patient outcomes has recently been identified as the target for an African-specific protein-truncating PCa-risk allele.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 25, 2023
Source ID
10.1038/s41391-023-00722-x

Entities

People

  • Christopher A. Haiman
  • Jue Jiang
  • M. S. Riana Bornman
  • Pxy Soh
  • Shingai B. A. Mutambirwa
  • Vanessa Hayes
  • Weerachai Jaratlerdsiri

Organizations

  • Congressionally Directed Medical Research Programs
  • National Health and Medical Research Council

Tags

Fields of Study

  • Medicine

Readers

  • Molecular and genetic basis of cancer.
  • Prostate Cancer Biology.