Acid-suppressive medications and risk of colorectal cancer: results from three large prospective cohort studies
Abstract
Despite several plausible biological mechanisms linking proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) with colorectal tumorigenesis, their association with risk of colorectal cancer (CRC) has not been adequately assessed in prospective epidemiological studies.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 16, 2020
- Source ID
- 10.1038/s41416-020-0939-y
Entities
People
- Ana Babic
- Andrew T Chan
- Brian M. Wolpin
- Charles S. Fuchs
- Chen Yuan
- Edward L. Giovannucci
- Hamed Khalili
- Kana Wu
- Kimmie Ng
- Meir J. Stampfer
- Natalia Khalaf
- Paul Lochhead
- Shuji Ogino
- Vicente Morales-oyarvide
- Xuehong Zhang
Organizations
- American Cancer Society
- Cancer Research UK
- Crohn's & Colitis Foundation of America
- National Institutes of Health
- United States Department of Defense
- United States Department of Health and Human Services