Endogenous estrogen receptor modulating oxysterols and breast cancer prognosis: Results from the MARIE patient cohort

Abstract

27-hydroxycholesterol (HC) and 25-HC were identified as endogenous selective estrogen receptor modulators (SERMs) and estrogen receptor (ER) modulators, respectively. They are hypothesized to play a role in multiple physiologic processes and pathologies, including breast cancer development and progression.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 24, 2023
Source ID
10.1038/s41416-023-02315-w

Entities

People

  • Jenny Chang-Claude
  • Nadia Obi
  • Nina Sophia Decker
  • RenĂ©e Turzanski Fortner
  • Rudolf Kaaks
  • Sabine Behrens
  • Theron Johnson

Organizations

  • United States Department of Defense

Tags

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Breast cancer cell signaling and growth regulation.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.