Imaging brain activity during complex social behaviors in Drosophila with Flyception2
Abstract
Optical in vivo recordings from freely walking Drosophila are currently possible only for limited behaviors. Here, we expand the range of accessible behaviors with a retroreflective marker-based tracking and ratiometric brain imaging system, permitting brain activity imaging even in copulating male flies. We discover that P1 neurons, active during courtship, are inactive during copulation, whereas GABAergic mAL neurons remain active during copulation, suggesting a countervailing role of mAL in opposing P1 activity during mating.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 30, 2020
- Source ID
- 10.1038/s41467-020-14487-7
Entities
People
- Dhruv Grover
- Jinfang Li
- Ralph J. Greenspan
- Takeo Katsuki
- Thomas J. Dawkins
Organizations
- Air Force Office of Scientific Research