Microengineered peripheral nerve-on-a-chip for preclinical physiological testing
Abstract
A microscale, organotypicin vitromodel of sensory peripheral nerve tissue may be assessed with clinically-relevant morphological and physiological measures for use as a drug screening assay for selecting promising lead compounds with higher chances of late-stage success.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2015
- Source ID
- 10.1039/c4lc01513d
Entities
People
- Benjamin J. Hall
- J. Lowry Curley
- Michael J Moore
- Oliver H. Miller
- Renee M. Huval
- Yuwei Fan
Organizations
- Division of Chemical, Bioengineering, Environmental, and Transport Systems
- Tulane University of Louisiana
- United States Army
- United States Army Medical Research and Development Command