Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status
Abstract
This study uses an untargeted metabolomics approach to identify changes in energetic processes underlying Huntington's disease pathogenesis and Mn neurotoxicity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2015
- Source ID
- 10.1039/c4mt00223g
Entities
People
- Aaron B. Bowman
- Cody R. Goodwin
- John A. McLean
- Julia Bornhorst
- Kevin K. Kumar
- Michael A. Uhouse
- Michael Aschner
- Tanja Schwerdtle
Organizations
- Albert Einstein College of Medicine
- Defense Threat Reduction Agency
- National Center for Advancing Translational Sciences
- National Institute of Environmental Health Sciences
- National Institute of General Medical Sciences
- University of Potsdam
- Vanderbilt University
- Yusuf Hamied Department of Chemistry