Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages

Abstract

Mannosylated nanoparticles are capable of delivering nucleotide sequences to tumor associated macrophages (TAMs) and have enhancedin vivouptake in TAMs.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2015
Source ID
10.1039/c4nr03962a

Entities

People

  • Bharat Kumar
  • Fiona E. Yull
  • Ian D. Mcfadden
  • Oleg Tikhomirov
  • Ryan A. Ortega
  • Todd D. Giorgio
  • Whitney J. Barham

Organizations

  • Congressionally Directed Medical Research Programs
  • Vanderbilt University
  • Vanderbilt-Ingram Cancer Center

Tags

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Molecular Genetics
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech