Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2′-alkylated RNA monomers
Abstract
Energetically activated double-stranded probes with interstrand arrangements of intercalator-functionalized nucleotides enable recognition of mixed-sequence DNA with single nucleotide fidelity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2014
- Source ID
- 10.1039/c4ob01183j
Entities
People
- Andreas S. Madsen
- Bradley C. Gibbons
- Dale C. Guenther
- Patrick J. Hrdlicka
- Saswata Karmakar
Organizations
- Brigham Young University–Idaho
- National Center for Research Resources
- National Institute of General Medical Sciences
- Office of Naval Research
- Technical University of Denmark
- University of Idaho
- Yusuf Hamied Department of Chemistry