Mass spectrometry of modified RNAs: recent developments
Abstract
A common feature of ribonucleic acids (RNAs) is that they can undergo a variety of chemical modifications, all of which can be detected by mass spectrometry. Here we highlight recent analytical developments in the field, which now enable quantitative characterization of complex mixtures of modified RNAs.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2016
- Source ID
- 10.1039/c5an01797a
Entities
People
- Collin Wetzel
- Patrick A. Limbach
Organizations
- Defense Threat Reduction Agency
- Division of Chemistry
- National Institutes of Health
- United States Army
- University of Cincinnati
- Yusuf Hamied Department of Chemistry