Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis
Abstract
Using experimental and computational approaches to define sequence-level design principles that enable rationally improved closure and tweezer-actuated enzyme function of a DNA tweezer.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2016
- Source ID
- 10.1039/c5nr07263h
Entities
People
- Hao Yan
- Mark Bathe
- Matthew R. Adendorff
- Minghui Liu
- Nils G. Walter
- Soma Dhakal
Organizations
- Arizona State University
- Army Research Office
- Biodesign Institute
- Massachusetts Institute of Technology
- University of Michigan
- Yusuf Hamied Department of Chemistry