Locked nucleic acid (LNA) induced effect on the hybridization and fluorescence properties of oligodeoxyribonucleotides modified with nucleobase-functionalized DNA monomers
Abstract
Mixmer oligonucleotides modified with LNA and C5-pyrene-functionalized DNA monomers are shown to display interesting fluorescence properties for the discrimination of single nucleotide polymorphisms (SNPs).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2015
- Source ID
- 10.1039/c5ob00860c
Entities
People
- Mamta Kaura
- Patrick J. Hrdlicka
Organizations
- Office of Naval Research
- United States Army
- University of Idaho
- Yusuf Hamied Department of Chemistry