Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

Abstract

Optimized Invader probes enable efficient (C50 t50 24 h), and single nucleotide specific recognition of DNA targets.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2015
Source ID
10.1039/c5sc01238d

Entities

People

  • Bradley A. Didion
  • Brooke A. Anderson
  • Dale C. Guenther
  • Grace H. Anderson
  • John P. Verstegen
  • Patrick J. Hrdlicka
  • Saswata Karmakar
  • Wei Guo

Organizations

  • National Center for Research Resources
  • National Institute of General Medical Sciences
  • Office of Naval Research
  • United States Army
  • University of Idaho
  • Yusuf Hamied Department of Chemistry

Tags

Readers

  • Molecular Genetics