Identifying potential protein targets for toluene using a molecular similarity search, in silico docking and in vitro validation

Abstract

The toxicity of chemicals greatly depends on their interaction with macromolecular targets.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2015
Source ID
10.1039/c5tx00009b

Entities

People

  • C. A. Mauzy
  • J. M. Gearhart
  • J. S. Frey
  • R. R. Chapleau
  • Y. G. Chushak

Organizations

  • 711th Human Performance Wing
  • Air Force Research Laboratory
  • Defense Threat Reduction Agency
  • Henry M. Jackson Foundation for the Advancement of Military Medicine
  • United States Army

Tags

Fields of Study

  • Chemistry