Dynamics of human acetylcholinesterase bound to non-covalent and covalent inhibitors shedding light on changes to the water network structure

Abstract

Active site gorge of hAChE in complex with HupA (A) or phosphonylated by aged soman (B).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2016
Source ID
10.1039/c6cp00280c

Entities

People

  • Florian Nachon
  • Judith Peters
  • Kévin Scannapieco
  • Marie Trovaslet
  • Michael Marek Koza
  • Nicolas Martinez
  • Patrick Masson

Organizations

  • Armed Forces Biomedical Research Institute
  • Defense Threat Reduction Agency
  • Grenoble Alpes University
  • Institut Laue–Langevin
  • Kazan Federal University
  • Laboratoire Interdisciplinaire de Physique

Tags

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Neurotoxicology