Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag
Abstract
A novel approach utilizing a chemically cleavable Dde-based tag is employed herein to quantitatively label and releaseO-GlcNAcylated proteins for the mass spectrometric identification of previously unknown glycosylation sites.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2016
- Source ID
- 10.1039/c6mb00138f
Entities
People
- Courtney L. Jenkins
- Daniel E. Mason
- Elizabeth H. Jensen
- Eric C. Peters
- Linda C. Hsieh-wilson
- Matthew E. Griffin
- Shannon E. Stone
Organizations
- California Institute of Technology
- National Institutes of Health
- National Science Foundation
- Novartis
- United States Army
- United States Department of Defense
- Yusuf Hamied Department of Chemistry