Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase
Abstract
Expanding the chemical diversity of threose nucleic acid (TNA) beyond the natural bases would enable the development of TNA polymers with enhanced physicochemical properties.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2018
- Source ID
- 10.1039/c7cc09130c
Entities
People
- Hui Mei
- John C Chaput
Organizations
- Defense Advanced Research Projects Agency
- National Science Foundation
- United States Army
- University of California
- University of California, Irvine