Evaluation of de novo-designed coiled coils as off-the-shelf components for protein assembly

Abstract

Coiled coils are effective at oligomerizing larger proteins, but oligomerization states may change unless care is taken to optimize design.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2017
Source ID
10.1039/c7me00012j

Entities

People

  • Aaron Sciore
  • Ajitha S. Cristie-david
  • Brandon T. Ruotolo
  • James C. A. Bardwell
  • Joseph D. Escheweiler
  • Neil Marsh
  • Philipp Koldewey
  • Somayesadat Badieyan

Organizations

  • Army Research Office
  • United States Army
  • University of Michigan
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Physics

Readers

  • Electrical Engineering
  • Molecular Biology and Genetics