Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers

Abstract

Evolved DNA polymerases are used in selections with fully 2′-OMe modified libraries to identify aptamers with high affinity for HNE.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jan 01, 2017
• Source ID: 10.1039/c7sc03747c

Entities

People

• Floyd E Romesberg
• Tingjian Chen
• Zhixia Liu

Organizations

• Defense Advanced Research Projects Agency
• Scripps Research
• United States Army
• Yusuf Hamied Department of Chemistry