Site-selective bromination of sp3 C–H bonds
Abstract
A method for converting sp3 C–H to C–Br bonds using an N-methyl sulfamate directing group is described. For all sulfamates examined, bromination occurs with high selectivity at the γ-carbon, affording a predictable method for C–H bond halogenation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2018
- Source ID
- 10.1039/c7sc04611a
Entities
People
- J. Du Bois
- Noah Z Burns
- Richard Zare
- Shibdas Banerjee
- Shyam Sathyamoorthi
Organizations
- Air Force Office of Scientific Research
- Division of Chemistry
- Indian Institute of Science Education and Research, Tirupati
- Stanford University
- United States Army
- Yusuf Hamied Department of Chemistry