Tuning of protease resistance in oligopeptides through N-alkylation

Abstract

In this work we demonstrate a strategy for tuning proteolysis of oligopeptides by expanding the N-alkylation of peptides beyond the common methyl group.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jan 01, 2018
• Source ID: 10.1039/c8cc04407d

Entities

People

• Athina Anastasaki
• Craig Hawker
• Revital Kaminker
• Sang-Ho Lee
• Will R Gutekunst
• Yingdong Luo

Organizations

• Center for Scientific Review
• Defense Advanced Research Projects Agency
• European Commission
• National Science Foundation
• United States Army
• University of California
• Yusuf Hamied Department of Chemistry