The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state
Abstract
As cholesterol fraction increases, ligand-bound receptor occupies more vesicle surface area, demonstrating co-localization with the cholesterol-rich phase.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1039/c8cc10130b
Entities
People
- Jacob Deyell
- Kate L White
- Lucia C. Dalle Ore
- M. Gertrude Gutierrez
- Noah Malmstadt
- Raymond C. Stevens
- Vadim Cherezov
Organizations
- Achievement Rewards for College Scientists Foundation
- National Institutes of Health
- Office of Naval Research
- United States Army
- University of Southern California
- Yusuf Hamied Department of Chemistry