Reversibly disulfide cross-linked micelles improve the pharmacokinetics and facilitate the targeted, on-demand delivery of doxorubicin in the treatment of B-cell lymphoma
Abstract
Disulfide cross-linked micellar formulation significantly improved the pharmacokinetics, tumor targeting, and anti-tumor efficacy of doxorubicin against B-cell lymphoma.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2018
- Source ID
- 10.1039/c8nr00680f
Entities
People
- Hongyong Zhang
- Joyce S. Lee
- Kai Xiao
- Kit S. Lam
- Li Lai
- Nasir Al Awwad
- Qiangqiang Liu
- Yan Luo
- Yuanpei Li
Organizations
- National Institutes of Health
- National Natural Science Foundation of China
- Sichuan University
- United States Army
- United States Department of Defense
- University of California, Davis
- West China Hospital