Targeting myeloid regulators by paclitaxel-loaded enzymatically degradable nanocups

Abstract

Carbon nanomaterial assisted delivery of paclitaxel to circulating and lymphoid tissue MDSC as proof of concept immunotherapy strategyin vivo.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2018
Source ID
10.1039/c8nr04437f

Entities

People

  • Alexander Star
  • David L. White
  • Galina V. Shurin
  • Michael R. Shurin
  • Oleksandr Kapralov
  • Seth C Burkert
  • Valerian E. Kagan
  • Xiaoyun He

Organizations

  • Division of Chemistry
  • National Cancer Institute
  • National Institute of Environmental Health Sciences
  • Office of Naval Research
  • United States Army
  • University of Pittsburgh
  • University of Pittsburgh Medical Center
  • Yusuf Hamied Department of Chemistry

Tags

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Nanocomposite Materials Science
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech