Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity

Abstract

Dual-targeted liposomes achieve increased uptake and selectivity for multiple myeloma cells through cooperative peptide targeting of LPAM-1 and VLA-4.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2019
Source ID
10.1039/c8nr09431d

Entities

People

  • Basar Bilgicer
  • David Thomas Omstead
  • Jared Francis Stefanick
  • Tanyel Kiziltepe

Organizations

  • Congressionally Directed Medical Research Programs
  • Leukemia Research Foundation
  • United States Army
  • University of Notre Dame
  • Walther Cancer Foundation

Tags

Readers

  • Maritime and Naval Warfare Studies
  • Molecular and Cellular Biochemistry
  • Oncology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech