High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
Abstract
We report the development, validation, and application of an easy-to-use microfluidic micropipette aspiration device and automated image analysis platform that enables high-throughput measurements of the viscoelastic properties of cell nuclei.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1039/c9lc00444k
Entities
People
- Denis Aubry
- Emily S. Bell
- Gregory R Fedorchak
- Jan Lammerding
- Patricia M Davidson
- Philipp Isermann
- Rachele Allena
- Solenne Mondésert-deveraux
Organizations
- CentraleSupélec
- Congressionally Directed Medical Research Programs
- Cornell University
- Division of Chemical, Bioengineering, Environmental, and Transport Systems
- Division of Molecular & Cellular Biosciences
- Fondation ARC pour la recherche sur le cancer
- Meinig School of Biomedical Engineering
- National Cancer Institute
- National Heart, Lung, and Blood Institute
- National League Against Cancer
- Paris-Saclay University
- ParisTech
- United States Army
- Weill Institute for Cell and Molecular Biology