How mithramycin stereochemistry dictates its structure and DNA binding function

Abstract

The crystal structures of mithramycin and its analogue reveal how the chemistry of mithramycin shapes it for DNA binding.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2019
Source ID
10.1039/c9md00100j

Entities

People

  • Caixia Hou
  • Jürgen Rohr
  • Oleg V Tsodikov
  • Sean R Parkin

Organizations

  • National Institutes of Health
  • National Science Foundation
  • United States Army
  • United States Department of Defense
  • University of Kentucky
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Chemistry