Correlations between secondary structure- and protein–protein interface-mimicry: the interface mimicry hypothesis
Abstract
Preferred conformations of several peptidomimetics (specifically, minimalist mimics) were elucidated and compared with protein-protein interfaces on a huge scale, leading to a hypothesis regarding how these compounds mimic protein interface segments.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1039/c9ob00204a
Entities
People
- Chen-Ming Lin
- Jaru Taechalertpaisarn
- Kevin Burgess
- Lisa M Pérez
- Maritess Arancillo
- Rui-Liang Lyu
- Thomas R. Ioerger
Organizations
- Cancer Prevention and Research Institute of Texas
- Department of Computer Science, University of Oxford
- National Institutes of Health
- National Science Foundation
- Robert A. Welch Foundation
- Texas A&M University
- United States Army
- United States Department of Defense
- Yusuf Hamied Department of Chemistry