Synthetic mimics of cyclic antimicrobial peptides via templated ring-opening metathesis (TROM)
Abstract
We utilized a templated ring-opening metathesis (TROM) strategy to synthesize a series of precision macrocyclic olefins, each containing two, three or four repeating units of a cyclooctene with pendant carboxylic acid side chains.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2019
- Source ID
- 10.1039/c9py01271k
Entities
People
- Cansu Ergene
- Edmund Palermo
- Zhe Zhou
Organizations
- Army Research Office
- Division of Materials Research
- Rensselaer Polytechnic Institute
- Troy University
- United States Army