Computational design of syntheses leading to compound libraries or isotopically labelled targets

Abstract

Network-search routines over large graphs of retrosynthetic scenarios are adapted to multi-target design operating on one common search graph enabling design of syntheses of compound libraries or isotopically labelled targets.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2019
Source ID
10.1039/c9sc02678a

Entities

People

  • Bartosz Andrzej Grzybowski
  • Karol Molga
  • Piotr Dittwald

Organizations

  • Center for Soft and Living Matter
  • Defense Advanced Research Projects Agency
  • Institute of Organic Chemistry
  • Korea Basic Science Institute
  • Polish Academy of Sciences

Tags

Fields of Study

  • Computer science

Readers

  • Graph Algorithms and Convex Optimization.
  • Molecular and Cellular Biochemistry
  • Systems Analysis and Design