Glutathione triggered degradation of polydopamine to facilitate controlled drug release for synergic combinational cancer treatment

Abstract

Here we report a novel mechanism for triggering drug release in the polydopamine (PDA)-coated magnetic CuCo2S4 core–shell nanostructure by glutathione (GSH) triggered degradation of PDA for release.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2019
Source ID
10.1039/c9tb01400d

Entities

People

  • An-qi Zheng
  • Jian-Hua Wang
  • Omar Johnson
  • Ting-ting Guo
  • Wei Chen
  • Ya-nan Hao
  • Yang Shu

Organizations

  • National Cancer Institute
  • National Institutes of Health
  • National Natural Science Foundation of China
  • Northeastern University
  • United States Army
  • University of Texas at Arlington
  • Yusuf Hamied Department of Chemistry

Tags

Readers

  • Nanocomposite Materials Science
  • Oncology (Cancer Research).
  • Toxicology/Environmental Toxicology

Technology Areas

  • Microelectronics