High-throughput screening of organic reactions in microdroplets using desorption electrospray ionization mass spectrometry (DESI-MS): hardware and software implementation

Abstract

Implementation of a novel method for high-throughput screening of reactions in microdroplets. The reaction and analysis steps are performed simultaneously using desorption electrospray ionization mass spectrometry (DESI-MS) at a rate of up to 1 reaction mixture per second.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2020
Source ID
10.1039/d0ay00072h

Entities

People

  • Andy Koswara
  • Botond Szilágyi
  • Bradley P. Loren
  • Christina R Ferreira
  • David H. Thompson
  • David L. Logsdon
  • Larisa Avramova
  • R. Graham Cooks
  • Richard S. Hosler
  • Ryan T. Hilger
  • Tiago Jose P. Sobreira
  • Zinia Jaman
  • Zoltan K Nagy

Organizations

  • Defense Advanced Research Projects Agency
  • Purdue University
  • United States Army
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Chemistry

Readers

  • Aerospace Propulsion Engineering.
  • Oncology and Biomarker-Based Cancer Detection.
  • Organic Chemistry