Ribosomal incorporation of cyclic β-amino acids into peptides using in vitro translation

Abstract

We demonstrate in vitro incorporation of cyclic β-amino acids into peptides by the ribosome through genetic code reprogramming.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2020
Source ID
10.1039/d0cc02121k

Entities

People

  • Andrew D Ellington
  • Do Soon Kim
  • James D. Austin
  • Joongoo Lee
  • Michael C Jewett
  • Michelle Byrom
  • Rafael Torres

Organizations

  • Army Research Office
  • National Science Foundation
  • Northwestern University
  • United States Army
  • University of Texas at Austin
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Biology
  • Computer science

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech