Precursor-directed biosynthesis of catechol compounds in Acinetobacter bouvetii DSM 14964
Abstract
Genome mining for VibH homologs reveals several Acinetobacter species with a gene cluster putatively encoding biosynthesis of catechol siderophores with an amine core. Enzyme flexibility allows for in vivo synthesis of non-native catechol compounds.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2020
- Source ID
- 10.1039/d0cc04171h
Entities
People
- Alison Butler
- Zachary L Reitz
Organizations
- Army Research Office
- National Science Foundation
- United States Army
- University of California
- Yusuf Hamied Department of Chemistry