Design of small molecules targeting RNA structure from sequence
Abstract
Herein, we describe methods to identify structured regions within disease-causing RNAs and to design lead small molecules that selectively bind these structures to modulate function.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2020
- Source ID
- 10.1039/d0cs00455c
Entities
People
- Alicia J. Angelbello
- Andrei Ursu
- Collin A O'Leary
- Jessica L. Childs-disney
- Matthew D Disney
- Ryan J Andrews
- Samantha M. Meyer
- Walter N. Moss
Organizations
- Iowa State University
- National Cancer Institute
- National Institute of General Medical Sciences
- National Institute of Neurological Disorders and Stroke
- Scripps Research
- United States Army
- United States Department of Defense
- Yusuf Hamied Department of Chemistry