Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells
Abstract
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2020
- Source ID
- 10.1039/d0lc00069h
Entities
People
- John Michael Ramsey
- Nathan A. Siegfried
- W. Hampton Henley
Organizations
- Defense Advanced Research Projects Agency
- United States Army
- University of North Carolina at Chapel Hill
- Yusuf Hamied Department of Chemistry