Investigations on T cell transmigration in a human skin-on-chip (SoC) model

Abstract

Our skin-on-chip (SoC) model uniquely enabled quantitative studies of transendothelial and transepithelial migration of human T lymphocytes under mimicked inflammatory skin conditions and was used to test new drug candidates.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2021
Source ID
10.1039/d0lc01194k

Entities

People

  • Anthony E. Getschman
  • Brian F Volkman
  • David E Levin
  • Francis Lin
  • Jasmine Cheng
  • Min Zhao
  • Samuel Hwang
  • Song Liu
  • Susy Santos
  • Thomas Klonisch
  • Xiaoou Ren

Organizations

  • Air Force Office of Scientific Research
  • Defense Advanced Research Projects Agency
  • Medical College of Wisconsin
  • National Institutes of Health
  • National Psoriasis Foundation
  • Natural Sciences and Engineering Research Council
  • United States Army
  • University of California, Davis
  • University of Manitoba
  • University of Wisconsin–Milwaukee

Tags

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Computational Modeling and Simulation
  • Infectious Disease/Epidemiology