Chemical modulation of Kv7 potassium channels

Abstract

This review describes the synthetic and medicinal chemistry of small molecule modulators of the voltage-gated Kv7 (KCNQ) potassium channels and the available data of their biological and clinical properties.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2021
Source ID
10.1039/d0md00328j

Entities

People

  • Matteo Borgini
  • Peter Wipf
  • Pravat Mondal
  • Ruiting Liu

Organizations

  • United States Army
  • United States Department of Defense
  • University of Pittsburgh
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Chemistry

Readers

  • Electronics Engineering
  • Molecular Photonics/Laser Physics
  • Neuroscience